研究業績

2020年

フェアリー化合物

• "Safety evaluation of 2-aza-8-oxohypoxanthine based on in vitro and human patch tests"
  Aoshima, H., Hyodo, S., Ibuki, R., Wu, J., Choi, J-H., Kawagishi, H.
  Fundam. Toxicol. Sci. 7, 5, 207-215 (2020).
• "Biosynthesis of the fairy chemicals, 2-azahypoxanthine and imidazole-4-carboxamide, in the fairy ring-forming fungus Lepista sordida"
  Ito, A., Choi, J-H., Takemura,H., Kotajima,M., Wu, J., Tokuyama, S., Hirai, H., Asakawa, Ouchi, H., Inai, M., Kan, T., and Kawagishi, H.
  J. Nat. Prod. 83, 2469-276 (2020).

キノコの機能性成分

• "A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis"
  D’Alessandro-Gabazza, C., Kobayashi, T., Yasuma, T., Toda, M., Kim, H., Fujimoto, H., Hataji, O., Takeshita, A., Nishihama, K., Okano, Y., Okano, Y., Nishii, Y., Tomaru, A., Fujiwara, K., D'Alessandro, V. F., Abdel-Hamid, A., Ren, Y., Pereira, G., Wright, C., Hernandez, A., Fields, C., Yau, P., Wang, S., Mizoguchi, A., Fukumura, M., Ohtsuka, J., Nosaka, T., Kataoka, K., Kondoh, Y., Wu, J., Kawagishi, H., Yano, Y., Mackie, R., Cann, I., and Gabazza, E. C.
  Nature Commun. 11, 1539 (2020).

  • DOI: 10.1038/s41467-020-15344-3
• "A biomimetic synthesis of chaxine and its related compounds"
  Niki, M., Hirata, Y., Nakazaki, A., Wu, J., Kawagishi, H., and Nishikawa, T.
  J. Org. Chem. 85, 7, 4848-4860 (2020).

  • DOI: 10.1021/acs.joc.9b03482
• "Effects of imidazole-4-carboxamide and 2-azahypoxanthine on the growth of Pinus densiflora seedlings and its ectomycorrhizal formation with Tricholoma matsutake"
  Nakano, S., Yamanaka, T., and Kawagishi, H.
  Mycoscience 61, 5, 259-263 (2020).
• "Bitter compounds in two Tricholoma species, T. aestuans and T. virgatum"
  Oba, Y., Urai, M., Wu, J., Tomizawa, M., Kawagishi,H., and Hashimoto, K.
  J. Antibiotic. 73, 697-701 (2020).

  • DOI: 10.1038/s41429-020-0338-x
• "A fairy chemical suppresses retinal angiogenesis as a HIF inhibitor"
  Lee, D., Miwa, Y., Wu, J., Shoda, C., Jeong, H., Kawagishi, H., Tsubota, K., and Kurihara. T.
  Biomolecules 10, 1405 (2020).

  • DOI: 10.3390/biom10101405
• "Plant growth regulators and axl and immune checkpoint inhibitors from the edible mushroom Leucopaxillus giganteus"
  Malya, I. Y., Wu, J., Harada, E., Toda, M., D’Alessandro-Gabazza, C. N., Yasuma,T., Gabazza, E. C., Choi, J-H., Hirai, H., and Kawagishia, H.
  Biosci. Biotechnol. Biochem. 80, 1332-1338 (2020).
• "Axl and immune checkpoints inhibitors from the fruiting bodies of Pleurocybella porrigens"
  Ridwan, Y. A., Wu, J., Harada, E., D’Alessandro-Gabazza, C., Toda, M., Yasuma,T., Gabazza, E. C., Choi, J-H., Hirai, H., and Kawagishi, H.
  J. Antibiotic. 73, 733-736 (2020).
• "白色腐朽菌シイタケ由来エンド型 ポリガラクツロナーゼの精製と特性解析"
  田中裕基, 平間加那子, 鈴木智大, 羽生直人, 金野尚武
  日本きのこ学会誌 28, 123-128 (2020).
• "Non-destructive analysis of the moisture content in shiitake mushrooms (Lentinula edodes) using near-infrared imaging at 1450 nm"
  Shinoda K., Konno N., Suzuki T.
  Mycoscience 61, 235-239 (2020).
• "Starch-degrading enzymes from the brown-rot fungus Fomitopsis palustris"
  Tanaka Y., Konno N., Suzuki T., Habu N.
  Protein Expr. Purif. 170, 105609 (2020).
• "A GH family 28 endo-polygalacturonase from the brown-rot fungus Fomitopsis palustris: purification, gene cloning, enzymatic characterization and effects of oxalate"
  Tanaka Y., Suzuki T., Nakamura L., Nakamura M., Ebihara S., Kurokura T., Iigo M., Dohra H. Habu N., Konno N.
  Int. J. Biol. Macromol. 123, 108-116 (2020).
• "蛍光色素ローダミンBを用いたシイタケ子実体生長過程における水分経路の可視化"
  窪田敏和, 鈴木智大, 金野尚武, 二宮尚
  日本きのこ学会誌 26, 164-168 (2020).

バイオリファイナリー

• "木質バイオマスからのメタン発酵前処理に適した白色腐朽菌の選抜"
  日本きのこ学会誌 28, 2, 56-61 (2020).

木材腐朽

• "Self-fusion and fusion cell isolation of transformants derived from white rot fungus Phanerochaete sordida YK-624 by simple visual method"
  Mori T., Kondo O., Sumiya T., Kawagishi H., Hirai H.
  J. Biosci. Bioeng. 129, 2, 146-149 (2020).

総説・著書

• "Plant growth regulators from mushrooms"
  Wu, J., Kawagishi, H
  J Antibiotic 73, 657-665 (2020).

  • DOI: 10.1038/s41429-020-0352-z
• "キノコ由来の生物活性2次代謝産物に関する化学的研究"
  呉静，河岸洋和
  化学と生物 58, 4, 231-239 (2020).