研究業績

2021年

フェアリー化合物

• "An S-adenosylhomocysteine analogue of a fairy chemical, imidazole-4-carboxamide, as its metabolite in rice and yeast, and synthetic investigations of related compounds"
  Ouchi, H., Namiki, T., Iwamoto, K., Matsuzaki, N., Inai, M., Kotajima, M., Wu, J., Choi, J.-H., Kimura, Y., Hirai,H., Xie, X., Kawagishi, H., and Kan,T.
  J. Nat. Prod. 84, 453-458 (2021).

  • DOI: 10.2131/fts.8.123
• "Safety evaluation of 2-aza-8-oxohypoxanthine by in vitro skin sensitization and human tests"
  Aoshima, H., Matsumoto, T., Ibuki, R. and Kawagishi, H.
  Fundam. Toxicol. Sci. 8, 4, 123-133 (2021).

  • DOI: 10.3390/cosmetics8030083
• "Clinical evaluation of topical lotion containing 2-aza-8-oxohypoxanthine on skin barrier function against water loss"
  Aoshima, H., Ibuki, R., Ito, M., and Kawagishi, H.
  Cosmetics 8, 83 (2021).

キノコの機能性成分

• "An efficient heterologous Escherichia coli-based expression system for lectin production from Pleurocybella porrigens"
  Suzuki, T., Nakamura, L., Inayoshi, S., Tezuka, Y., Choi, J-H., Dohra, H., Sasanami, T. Hirai, H., and Kawagishi H.
  Biosci. Biotechnol. Biochem. 5, 630-633 (2021).
• "A new lanostane triterpenoid from the mushroom Hypholoma fasciculare"
  Wang, J, Wu, J., Tsutsumi, K., Choi, J.-H., Hirai, H., Kobori, H.,Takikawa, Y., and Kawagishi, H.
  Biosci. Biotechnol. Biochem. 86, 7, 819-823 (2021).

キノコ毒

• "Quantification of ustalic acid, a chemotaxonomic marker, in Tricholoma ustale using liquid chromatography_mass spectrometry"
  Ito,T., Nagai, H., Aoki, W., Yamada, A., Kawagishi, H., Fukaya, M., and Konishi, H.
  J. Nat. Med. 75, 688-691 (2021).

  • DOI: 10.1007/s11418-021-01496-z
• "An Efficient Heterologous Escherichia coli-Based Expression System for Lectin Production from Pleurocybella porrigens"
  Suzuki T., Nakamura L., Inayoshi S., Tezuka Y., Ono A., Choi J-H, Dohra H., Sasanami T., Hirai H., Kawagishi H.
  Biosci. Biotechnol. Biochem. 85, 630-633 (2021).

バイオリファイナリー

• "Improvement of saccharide yield from wood by simultaneous enzymatic delignification and saccharification using a ligninolytic enzyme and cellulase"
  Mori T., Ikeda K., Kawagishi H., Hirai H.
  J. Biosci. Bioeng. 132, 3, 213-219 (2021).

バイオレメディエーション

• "White-rot fungus Phanerochaete chrysosporium metabolizes chloropyridinyl-type neonicotinoid insecticides by an N-dealkylation reaction catalyzed by two cytochrome P450s"
  Mori T., Ohno H., Ichinose H., Kawagishi H., Hirai H.
  J. Hazard. Mater. 402, 123831 (2021).

ゲノム研究

• "Draft Genome Sequence of the White-Rot Fungus Phanerochaete sordida YK-624"
  T. Mori, H. Dohra, T. Suzuki, H. Kawagishi, H. Hirai
  Microbiol. Resour. Announc. 42, e0084221 (2021).
• "High-quality genome assembly of the soybean fungal pathogen Cercospora kikuchii"
  Kashiwa T, Suzuki T.
  Genes Genome. Genet. 27, jkab277 (2021).
• "Genetic sequence analysis and characterization of bioactive compounds in mushroom-forming fungi"
  Suzuki T.
  Biosci. Biotechnol. Biochem. 85, 8-12. (2021).

木材腐朽

• "Transcriptomics analysis reveals the high biodegradation efficiency of white-rot fungus Phanerochaete sordida YK-624 on native lignin"
  Wang J.*, Suzuki T.*, Mori T.*, Yin R., Dohra H., Kawagishi H., Hirai H. (*Equal contribution)
  J. Biosci. Bioeng. 132, 3, 253-257 (2021).

総説・著書

• "きのこの生物活性と応用展開　第5章　フェアリー化合物の発見，基礎研究，そして実用化〜機能性化粧品原料としてのAOH製品開発〜"
  青島央江，河岸洋和
  河岸洋和（監修），シーエムシー出版, 352-359 (2021).
• "Chemical studies on bioactive compounds related to higher fungi"
  Kawagishi, H.
  Biosci. Biotechnol. Biochem. 85, 1, 1-7 (2021).

  • DOI: 10.1093/bbb/zbaa072